Evidence for effective interventions for children and young people with gender dysphoria—update

Claim:

We identified 17 studies pertaining to puberty suppression treatment (PS) in this Evidence Check update. Broadly, the newly identified evidence reinforced the previous finding regarding benefits and effectiveness. That is, PS agents (generally referred to as GnRHa) were reported to be safe, effective and reversible. [...] This Evidence Check update predominantly reinforces findings of the previous review, with research reporting that puberty suppression treatment is safe, effective and reversible. However, the strength of this evidence remains low.